R147 (E. coli numbering) is denoted as an acid/base catalytic residue. Suggest a possible mutation that could be engineered in this enzyme to confirm that R147 does in fact possess this function. You must justify your answer for any credit. Acid/Base Polaromonassp .. D L P G E H DW S S E K Y L L H T P K L F D A R Q A V 201 N. aromaticavorans .. S L P S V T G W D T R K A L N Y V P K L F E E L K T Y 201 E. coli . Q W P E E Q L W S T E K Y L D F M P K L F D A R N F F 203 E. caratovora C. beijerincki