Rank Movie Title Opening Gross 1 Toy Story 3 110,307,189 2 Alice in Wonderland (2010) 116,101,023 3 Iron Man 2 128,122,480 4 The Twilight Saga: Eclipse 64,832,191 5 Harry Potter and the Deathly Hallows Part 1 125,017,372 6 Inception 62,785,337 7 Despicable Me 56,397,125 8 Shrek Forever After 70,838,207 9 How to Train Your Dragon 43,732,319 10 Tangled 48,767,052 11 The Karate Kid 55,665,805 12 Tron Legacy 44,026,211 13 True Grit 24,830,443 14 Clash of the Titans (2010) 61,235,105 15 Grown Ups 40,506,562 16 Little Fockers 30,833,665 17 Megamind 46,016,833 18 The King's Speech 355,450 19 The Last Airbender 40,325,019 20 Shutter Island 41,062,440 21 The Other Guys 35,543,162 22 Salt 36,011,243 23 Jackass 3-D 50,353,641 24 Valentine's Day 56,260,707 25 Black Swan 1,443,809 26 Robin Hood 36,063,385 27 The Chronicles of Narnia: The Voyage of the Dawn Tr 24,005,069 28 The Expendables 34,825,135 29 Due Date 32,689,406 30 Yogi Bear 16,411,322 31 Date Night 25,207,599 32 The Social Network 22,445,653 33 Sex and the City 2 31,001,870 34 The Book of Eli 32,789,494 35 The Fighter 300,010 36 The Town 23,808,032 37 Prince of Persia: The Sands of Time 30,095,259 38 Red 21,761,408 39 Percy Jackson & The Olympians: The Lightning Thief 31,236,067 40 Paranormal Activity 2 40,678,424 41 Unstoppable 22,688,457 42 Eat Pray Love 23,104,523 43 Dear John 30,468,614 44 The A-Team 25,669,455 45 Knight & Day 20,139,985 Total Gross 415,004,880 334,191,110 312,433,331 300,531,751 295,983,305 292,576,195 251,513,985 238,736,787 217,581,231 200,821,936 176,591,618 172,062,763 171,243,005 163,214,888 162,001,186 148,438,600 148,415,853 135,453,143 131,772,187 128,012,934 119,219,978 118,311,368 117,229,692 110,485,654 106,954,678 105,269,730 104,386,950 103,068,524 100,539,043 100,246,011 98,711,404 96,962,694 95,347,692 94,835,059 93,617,009 92,186,262 90,759,676 90,380,162 88,768,303 84,752,907 81,562,942 80,574,010 80,014,842 77,222,099 76,423,035 46 Dinner for Schmucks 47 The Tourist 48 The Bounty Hunter 49 Diary of a Wimpy Kid 50 The Sorcerer's Apprentice 51 A Nightmare on Elm Street (2010) 52 The Last Song 53 The Wolfman 54 Get Him to the Greek 55 Resident Evil: Afterlife 56 Tyler Perry's Why Did I Get Married Too? 57 Tooth Fairy 58 Secretariat 59 Easy A 60 Takers 61 Legend of the Guardians: The Owls of Ga'Hoole 62 Life as We Know It 63 Letters to Juliet 64 Wall Street: Money Never Sleeps 65 Predators 66 Hot Tub Time Machine 67 Kick-Ass 68 Killers 69 Saw 3D 70 Cop Out 71 Cats & Dogs: The Revenge of Kitty Galore 72 Edge of Darkness 73 Gulliver's Travels 74 Death at a Funeral (2010) 75 Step Up 3-D 76 The Last Exorcism 77 Hubble 3D 78 Legion (2010) 79 Burlesque 80 The Crazies 81 For Colored Girls 82 The Back-Up Plan 83 Vampires Suck 84 The American 85 Green Zone 86 Marmaduke 87 Devil 88 Hereafter 89 When in Rome 90 Love and Other Drugs 91 She's Out of My League 23,527,839 16,472,458 20,686,423 22,126,166 17,619,622 32,902,299 16,007,426 31,479,235 17,570,955 26,650,264 29,289,537 14,010,409 12,694,770 17,734,040 20,512,304 16,112,211 14,506,464 13,540,486 19,011,188 24,760,882 14,020,502 19,828,687 15,837,266 22,530,123 18,211,126 12,279,363 17,214,384 6,307,691 16,217,540 15,812,311 20,366,613 413,477 17,501,625 11,947,744 16,067,552 19,497,324 12,201,710 12,202,831 13,177,790 14,309,295 11,599,661 12,289,375 220,322 12,350,041 9,739,161 9,775,278 73,026,337 67,631,157 67,061,228 64,003,625 63,150,991 63,075,011 62,950,384 61,979,680 60,974,475 60,128,566 60,095,852 60,022,256 59,713,955 58,401,464 57,744,720 55,675,313 53,374,681 53,032,453 52,474,616 52,000,688 50,287,556 48,071,303 47,059,963 45,710,178 44,875,481 43,585,753 43,313,890 42,779,261 42,739,347 42,400,223 41,034,350 40,408,090 40,168,080 39,440,655 39,123,589 37,729,698 37,490,007 36,661,504 35,606,376 35,053,660 33,644,788 33,601,190 32,746,941 32,680,633 32,367,005 32,010,860 92 Scott Pilgrim vs. the World 93 Charlie St. Cloud 94 Morning Glory 95 How Do You Know 96 Daybreakers 97 Nanny McPhee Returns 98 The Switch 99 Brooklyn's Finest 100 Machete 10,609,795 12,381,585 9,203,266 7,484,696 15,146,692 8,407,685 8,436,713 13,350,299 11,416,164 31,524,275 31,162,545 31,011,732 30,212,620 30,101,577 29,011,215 27,779,426 27,163,593 26,593,646 Theaters Weeks 4,028 24 3,739 18 4,390 15 4,468 16 4,125 20 3,792 25 3,602 28 4,386 16 4,060 17 3,603 27 3,740 15 3,451 17 3,464 18 3,802 16 3,534 18 3,675 12 3,949 16 2,584 18 3,203 12 3,356 16 3,651 15 3,612 14 3,139 14 3,665 12 2,407 22 3,505 12 3,555 18 3,398 10 3,365 12 3,515 16 3,380 22 2,921 22 3,445 12 3,111 17 2,534 16 2,935 16 3,646 17 3,349 16 3,396 20 3,239 13 3,261 17 3,108 12 3,062 12 3,544 14 3,104 15 3,046 2,756 3,118 3,083 3,504 3,332 2,794 3,223 2,702 3,209 2,155 3,345 3,108 2,974 2,206 3,575 3,150 2,975 3,597 2,669 2,771 3,065 2,859 2,808 3,150 3,705 3,066 3,089 2,459 2,439 2,874 151 2,476 3,037 2,479 2,127 3,280 3,233 2,833 3,004 3,213 2,811 2,424 2,456 2,458 2,958 11 13 16 22 15 11 15 7 10 8 10 22 18 14 12 17 16 15 12 14 11 11 11 5 12 12 10 16 12 13 6 189 8 11 12 11 13 12 9 8 15 9 13 11 12 10 2,820 2,725 2,544 2,483 2,523 2,798 2,017 1,939 2,678 8 7 10 6 5 10 13 11 11