recent nationwide study investigated the value of the prostate-specific antigen (PSA) blood test for the detection of prostate cancer among 100,000 men 50 years of age and older. Of the 686 men who tested positive on the PSA test, a total of 281 were ultimately diagnosed with prostate cancer, either by immediate needle biopsy or during 12 months of watchful waiting. An additional 45 men who tested negative on the PSA test were ultimately diagnosed with prostate cancer during 12 months of follow-up.

1) Set up the 2X2 contingency table for the data. 2) What is the sensitivity of the PSA test? Interpret the result. 3) What is the specificity of the PSA test? Interpret the result. 4) What is the positive predictive value (PPV) of the PSA test? Interpret the result. 5) What is the negative predictive value (NPV) of the PSA test? Interpret the result.