Answered step by step
Verified Expert Solution
Link Copied!

Question

1 Approved Answer

research group wants to compare a generic drug to a brand name drug. The response rate of the brand name drug is about 30%. Assume

research group wants to compare a generic drug to a brand name drug. The response rate of the brand name drug is about 30%. Assume the FDA will approve the generic drug if its response rate is not less than the response rate of the brand name drug by 5%. In addition, FDA wants to have high probability (i.e., 99%) to disapprove the generic drug when in fact its response rate is worse than that of the brand name drug by more than 5%. (a) [5 points] Please construct the null hypothesis and the alternative hypothesis using statistical notations. (b) [10 points] Assume equal allocation of patients to both treatment groups. How large should the sample size be in order to have 95% power to claim that the generic drug is as good as the brand name drug when in fact it is the case? The following information may be useful: z0.1 1.28, z0.05 1.64, z0.025 1.96, z0.01 2.33, z0.005 2.58. z is the 100(1 )th percentile of the N (0, 1)

Step by Step Solution

There are 3 Steps involved in it

Step: 1

blur-text-image

Get Instant Access to Expert-Tailored Solutions

See step-by-step solutions with expert insights and AI powered tools for academic success

Step: 2

blur-text-image

Step: 3

blur-text-image

Ace Your Homework with AI

Get the answers you need in no time with our AI-driven, step-by-step assistance

Get Started

Recommended Textbook for

Essential Calculus Early Transcendental Functions

Authors: Ron Larson, Robert P. Hostetler, Bruce H. Edwards

1st Edition

618879188, 618879182, 978-0618879182

More Books

Students also viewed these Mathematics questions