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Researchers are interested in testing the effectiveness of a new immunosuppressive therapy to be used post-transplant to reduce graft failure in the host. Suppose researchers

Researchers are interested in testing the effectiveness of a new immunosuppressive therapy to be used post-transplant to reduce graft failure in the host. Suppose researchers investigating this new therapy are concentrated about the dangerous side effects of the drug. For instance, participants that would like to enroll in the study are not allowed to already have diabetes, as the immunosuppressive agent has been found to drastically increase fasting glucose levels, which could be very dangerous for diabetics. This means, however, that participants that enter and are treated with the new drug may develop diabetes as time goes on. Suppose the following table addresses the incidence of diabetes in the study depending on treatment group. Use excel to answer the following questions.

What is the expected number of cases of Type II Diabetes among those using the best standard of care? (Round up to the nearest whole number)

Type II Diabetes

No Type II Diabetes

Total

Investigational Drug

41

27

68

Best Standard of Care

12

63

75

53

90

143

Carry out a formal chi-square test using the CHISQ.TEST in excel using the data in the table in the previous question. Is there an association between treatment group and type II diabetes?

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