Researchers Vogel et al. (JAMA, 2006) reported the following findings about the Study of Tamoxifen and Raloxifene (STAR), a study involving postmenopausal women who were at an increased risk for invasive breast cancer. Of the 9,726 women randomly assigned to use tamoxifen daily, 163 developed invasive breast cancer sometime during the next five years, compared to 168 in the group of 9,745 who were randomly assigned to use raloxifene daily.

use an appropriate applet to find the standardized statistic.