saturation low following surgery, and Kristy moaning and feeling sick due to surgical procedure and her pain score being 7 out of pain. As Kristy had medicine like fentanyl, propofol and midazolam when she was in procedure. Medicine like fentanyl used to reduce the extreme pain in during and after surgery. This drug activates mu-opioid receptors in central nervous system. It releases beta-endorphin which decrease the activity of central nervous system may leading some side effects like drowsiness, nausea, vomiting, dizziness, confusion, headache, and fatigue. In addition, propofol cause modulation of the inhibitory function of the neurotransmitter Gama-aminobutyric acid through GABA A receptors leading to rapid unconsciousness within few second resulting from quick distribution to plasma in central nervous system, this can also cause side effects like drowsiness and lowering blood pressure(). Vital signs