Serine proteases such as Chymotrypsin are incredibly important to cellular metabolism as they facilitate the break down of enzymes into smaller peptides. These enzymes work through an $8-$step mechanism in which a serine residue, with help of a histidine and aspartate, forms what is termed as a catalytic triad. The first step of chymotrypsin$$s mechanism is shown below.

Instructions

Using good old fashioned pen and paper $($pencil is ok too$),$ please fill in the remaining steps of the mechanism. Please include arrows for each step to indicate clearly what is happening in each part of the mechanism.Basic Concepts Worksheet $2\mathrm{.}2$

Description: Serine proteases such as Chymotrypsin are incredibly important to cellular

metabolism as they facilitate the breakdown of enzymes into smaller peptides. These enzymes

work through an $8-$step mechanism in which a serine residue, with help of a histidine and

aspartate, forms what is termed as a catalytic triad. The first step of chymotrypsin's mechanism

is shown below.

Instructions: Using good old fashioned pen and paper $($pencil is ok too$),$ please fill in the

remaining steps of the mechanism. Please include arrows for each step to indicate clearly what is

happening in each part of the mechanism.