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show your work please. 24. Valium target. y-Aminobutyric acid (GABA) opens chan- nels that are specific for chloride ions. The GABA, receptor channel is pharmacologically

show your work please.
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24. Valium target. y-Aminobutyric acid (GABA) opens chan- nels that are specific for chloride ions. The GABA, receptor channel is pharmacologically important because it is the target of diazepam (Valium), which is used to diminish anxiety. (a) The extracellular concentration of Cl- is 123 mM and the intracellular concentration is 4 mM. In which direction does Cl flow through an open channel when the membrane potential is in the - 60 mV to + 30 mV range? (b) What is the effect of Cl -channel opening on the excit- ability of a neuron? (c) The hydropathy profile of the GABA, receptor resem- bles that of the acetylcholine receptor. Predict the number of subunits in this Cl- channel

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