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Similar to Montgomery 6.4.9 An article in Nature Genetics [Treatment-specific Changes in Gene Expression Discriminate In Vivo Drug Response in Human Leukemia Cells (2003, Vol.
- Similar to Montgomery6.4.9 An article in Nature Genetics ["Treatment-specific Changes in Gene Expression Discriminate In Vivo Drug Response in Human Leukemia Cells" (2003, Vol. 34(1), pp. 85-90)] studied gene expression as a function of treatments for leukemia. One group received a high dose of the drug, while the control group received no treatment. Expression data (measures of gene activity) from one gene are shown below. Using below data create a report which graphically and statistically describes the data and then state if you think there is a difference between the 2 groups. What issues do you see in evaluating this data? This report should be no longer than 1 page of written text (no smaller than 11 font). Plus a maximum of 4 tables, graphs or figures (in total).
High Dose | Control |
19 | 389.2 |
159.2 | 644.3 |
62.2 | 1746.1 |
17 | 1535.3 |
146.7 | 1942.3 |
116.8 | 439.4 |
28.7 | 692.9 |
19.2 | 31.6 |
17.9 | 714.2 |
56.3 | 121.7 |
15.2 | 441.6 |
85.8 | 134 |
149.5 | 334.2 |
54.8 | 131.7 |
71.2 | 209.5 |
27.7 | 220.1 |
51.4 | 124.7 |
93.7 | 173.6 |
44.8 | 579.8 |
68.7 | 20.7 |
31.3 | 230 |
29.6 | 171.7 |
1074.3 | |
108.1 | |
935.2 | |
1029.1 | |
149.3 | |
41.8 | |
113.1 | |
847 | |
222.6 | |
26.5 | |
367.1 | |
254.4 | |
535 | |
203.7 | |
1132.6 | |
465.6 | |
830.5 | |
2659.2 | |
474.4 | |
218.1 | |
2958.5 | |
651.7 | |
345.1 | |
330.5 | |
460.3 | |
889.4 | |
3943.4 | |
87.9 | |
416.8 | |
3244.1 | |
237.6 | |
2726.8 | |
555.8 | |
246.4 | |
737.5 | |
195.3 | |
2781 | |
1697.6 | |
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