smoke yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes no no no no no no no no no no no no no no no no disease yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes sex male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male no no no no no no no no no yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes no no no no no no no no no no no no no no no no no no no no yes yes yes yes yes yes yes yes yes yes no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no yes male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male male female yes yes yes yes yes yes yes yes yes yes yes yes yes no no no no no no no no no no no no no no no no no no no no no no no no no no no no no yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes yes no no no no no no no no no no no no female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female yes yes yes yes yes yes yes no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no no female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female female