Someone please help.

Pyruvate kinase is allosterically activated by high concentrations of: A. True or B. False B. True or B. False C. True or B. False D. True or B. False E. True or B. False F. True or B. False Acetyl-CoA ATP Citrate Fructose 1,6-bisphosphate Fructose 2,6-bisphosphate glucose 6-phosphate The reciprocal regulation of glycolysis and gluconeogenesis by altered concentrations of fructose 2,6-bisphosphate occurs in which subcellular compartment, predominately of what type of cells? A. Cytoplasm of liver B. Cytoplasm of muscle C. Mitochondria of liver D. Mitochondria of muscle