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Testing a hypothesis: Does long working over 60 hours per week cause a new onset of depression symptoms. What statistical test would be best to

Testing a hypothesis: Does long working over 60 hours per week cause a new onset of depression symptoms.

What statistical test would be best to run on this when I have number of hours worked and they answers yes or no to reporting depressive symptoms?

Also what should be the level of significance tested in this study?

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