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The anhydride bond. shown below, is high energy upon hydrolysis because the electrophilic R group no longer competes for the C= the leaving group
The anhydride bond. shown below, is high energy upon hydrolysis because\ the electrophilic
R
group no longer competes for the
C=
\ the leaving group (
R
or
R^(')
) will be at a lower energy state.\ the competing resonance between the two carbonyls is relieved.\ the products have a lower entropy.
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