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The concentration C in milligrams per milliliter (mg/ml) of a certain drug in a person's blood-stream t hours after a pill is swallowed is modeled

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The concentration C in milligrams per milliliter (mg/ml) of a certain drug in a person's blood-stream t hours after a pill is swallowed is modeled by C(t) = 2+- 2t - -0.051 Estimate the change 143 in concentration when t changes from 40 to 50 minutes. The change in concentration is about mg/ml. (Type an integer or decimal rounded to the nearest thousandth as needed.)

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