The Court of Chancery granted a preliminary injunction to the plaintiffs, Mesa Petroleum Co., Mesa Asset Co., Mesa Partners II, and Mesa Eastern, Inc. (collectively "Mesa")^[1], enjoining an exchange offer of the defendant, Unocal Corporation (Unocal) for its own stock. The trial court concluded that a selective exchange offer, excluding Mesa, was legally impermissible. We cannot agree with such a blanket rule. The factual findings of the Vice Chancellor, fully supported by the record, establish that Unocal's board, consisting of a majority of independent directors, acted in good faith, and after reasonable investigation found that Mesa's tender offer was both inadequate and coercive. Under the circumstances the board had both the power and duty to oppose a bid it perceived to be harmful to the corporate enterprise. On this record we are satisfied that the device Unocal adopted is reasonable in relation to the threat posed, and that the board acted in the proper exercise of sound business judgment. We will not substitute our views for those of the board if the latter's decision can be "attributed to any rational business purpose."Sinclair Oil Corp. v. Levien,Del.Supr., 280 A.2d 717, 720 (1971). Accordingly, we reverse the decision of the Court of Chancery and order the preliminary injunction vacated.^[2]

Question 1

Please explain why thrombolytic therapy is not indicated in cases of

unstable angina and non-ST-segment elevation myocardial infarctions

(nSTE-MI) despite the fact that both nSTE-MI and ST-elevated MI

(STEMI) are caused by a thrombus for which thrombolytic therapy is

highly indicated? Could it be true that, in the case of unstable angina and

nSTE-MI has a higher incidence of intracranial haemorrhage than in the

case of ST-segment elevation MI?

Question 2

Doesn't the term 'acute coronary syndrome' include unstable angina, nonST-segment elevation myocardial infarctions and ST-elevated MI (STEMI)?1353

Question 3

Kindly mention the indications for clopidogrel in acute coronary

syndrome (ACS). Should it be used along with aspirin or alone if the

latter is contraindicated? Are there any studies that combine both

with either low-molecular-weight heparin (LMWH) or unfractionated

heparin? How long should clopidogrel be continued?

Question 4

What role do IV fluids play in the management of acute inferior wall

myocardial infarction?

Question 5

Is there any benefit in combining aspirin with clopidogrel in post-MI

angina and ischaemic stroke? A MATCH trial showed this combination

Question 6

If a young patient presents with hemiparesis and rheumatic atrial

fibrillation and is already on oral anticoagulant, with an international

normalized ratio (INR)3 and a normal computed tomography (CT)

scan done 2 hours after onset, should he receive heparin for prophylaxis

against further embolism? Should aspirin be combined with oral

anticoagulant later, or should target INR be increased?1363

Question 7

When treating mitral stenosis using a balloon valvotomy, how come no

thrombus develops at the site of the atrial septum or at the separated

commissure of the valve leaflets?

Question 8

Why does a mitral stenosis produce a loud S1?

Question 9

Why is the mitral valve more affected than any other valve in the heart in

most valvular diseases?

Question 10

What is William's syndrome (supravalvular obstruction)? Why does

hypercalcaemia occur with this syndrome?