The diffusion coefficient of a drug loaded in Ocusert device is 3.8 X 10-5 cm2/hr. The surface area of Ocusert is 0.8 cm2; the partition coefficient between the Ocusert and the tear fluid is 1.03; the thickness of the membrane is 0.7 mm; the solubility of the drug in water is 3.97 mg/cm3. Calculate the cumulative amount of drug released in 5 days