The emergence of plasmid-mediated New Delhi metallo--lactamase-1 (NDM-1) in carbapenem-resistant Gram-negative pathogens is an increasing clinical threat. What strategy will you use to design drugs

The emergence of plasmid-mediated New Delhi metallo-β-lactamase-1 (NDM-1) in carbapenem-resistant Gram-negative pathogens is an increasing clinical threat. What strategy will you use to design drugs for the therapy of the infections by the pathogens possessing NDM-1