The emerging of bacterial resistance has at least partly its foundation in the widespread use of antibiotics in humans and farm animals. Besides many other antibiotics, sulfonamides have been identified as emerging contaminants in the environment. Environmental fate of sulfonamides is determined by their acid-base characteristics and the pH of the environments e.g. the soil. N? SEO N H2N Figure 3. Sulfadiazine (from: Babic et al. TrAC, 2007, pka values 2.10 and 6.28). (a) Draw the pH-dependent species of sulfadiazine and indicate the equilibria (include pka values) between the different species. (b) Please sketch a fractional composition diagram for sulfadiazine, i.e. fraction of each species in dependence of pH. Please pay attention to the correct labeling of the axes (c) The pH value of soil at different locations can vary. For instance, for silty soil a pH value of approximately 5.5 and for sandy loam a pH -6.8 was measured. Which species do you expect will be the predominant species in these two different soil types