The equation for ATP hydrolysis is

ATP yields ADP + Pi delta G*= -30.5 kJ/mol

( H20)

(a) Calculate ?G for ATP hydrolysis to rank the following conditions from most favorable to least favorable. Assume a temperature of 37.0 ?C. R = 8.315 J/(mol?K).

ATP Hydrolysis most favorable

ATP hydroysis least favorable

The choices are:

muscle: [ATP]= 8.1mM; [ADP]= 0.9mM [Pi]= 8.1mM

brain: [ATP]= 2.6mM; [ADP]= 0.7mM [Pi]= 2.7mM

liver: [ATP]= 3.4mM; [ADP]= 1.3mM [Pi]= 4.8mM

(b) Calculate ?G for ATP hydrolysis in muscle at 18 ?C. Use the muscle concentrations from part a.

Delta g = kJ/mol