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The following kinetic resolutions have been performed to resolve the racemic alcohol shown below. OH (i) CalB Hexane 4 NAD+ enzymes A and B

 

 

The following kinetic resolutions have been performed to resolve the racemic alcohol shown below. OH (i) CalB Hexane 4 NAD+ enzymes A and B (1) 40%, 98% e.e. (ii) 78%, 98% e.e. (i) Reaction was carried out with Candida antarctica Lipase B alone. (ii) A catalytic quantity of NAD plus two enzymes A and B. 3. c) Propose two enzymes for A and B and discuss the required stereoselectivities. Why is no additional recycling system needed in this system? [3]

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