Question
The following kinetic resolutions have been performed to resolve the racemic alcohol shown below. OH (i) CalB Hexane 4 NAD+ enzymes A and B
The following kinetic resolutions have been performed to resolve the racemic alcohol shown below. OH (i) CalB Hexane 4 NAD+ enzymes A and B (1) 40%, 98% e.e. (ii) 78%, 98% e.e. (i) Reaction was carried out with Candida antarctica Lipase B alone. (ii) A catalytic quantity of NAD plus two enzymes A and B. 3. c) Propose two enzymes for A and B and discuss the required stereoselectivities. Why is no additional recycling system needed in this system? [3]
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Chemistry The Central Science
Authors: Theodore Brown, Eugene LeMay, Bruce Bursten, Catherine Murphy, Patrick Woodward
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321696727, 978-0132175081, 978-0321696724
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