The four changes that present challenges in management information systems $($MIS$)$ include the growth of cloud computing, the use of Big Data and the Internet of Things $($IoT$),$ the mobile platf and the application of to help managers understand their business and products.

A$.$ laws and regulations

B$.$ global positioning systems $($GPS$)$

C$.$ digital learning techniques

D$.$ artificial intelligence $($AI$)$

E$.$ local customs and cultures