The hydrolysis of ATP has an enthalpy and entropy of $-24\mathrm{.}3k\frac{J}{m}ol$ and $+21\mathrm{.}6J*K^{-1}*mo{l}^{-1},$ respectively, at $37C.$

What is the free energy change for the hydrolysis of $5$ mols of ATP?

Explain what contributes to the negative enthalpy change and positive entropy change in this reaction.

What physical characteristics of the reaction would change if an ATP hydrolase enzyme is added to the solution?