The table below contains PLASMA concentration-time data for a new medication (LIU987) following administration of a single IV bolus dose (250 mg). Below the
The table below contains PLASMA concentration-time data for a new medication (LIU987) following administration of a single IV bolus dose (250 mg). Below the table is a Ln C vs time plot of the data. Time (hr) Cp (ug/mL) Time (hr) Cp (ug/mL) 1 28.2 1 28.2 2 23.9 2 23.9 4 17.1 4 17.1 8 8.79 8 8.79 12 4.51 12 4.51 Ln Concentration (ug/mL) MO 53225 1 0.5 0 O O 2 6 Time (hr) O 8 What is the volume of distribution (in Liters)? 10 O 12
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Step: 2
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Authors: J. David Spiceland, James Sepe, Mark Nelson, Wayne Thomas
9th Edition
125972266X, 9781259722660
