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The table below from Putcha et al . ( 1 9 8 9 ) shows the average people ) plasma concentration of scopolamine over time
The table below from Putcha et al shows the average people plasma
concentration of scopolamine over time after intravenously injecting Scopolamine is a
drug used to treat motion sickness.
Using these concentration data points and the provided twocompartment pharmacokinetic
model equation, calculate the following:.
The volume of the central compartment
A The intercept of the distribution phase
B The intercept of the elimination phase
The rate constant governing transfer of drug from peripheral to central compartment
where
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