These are the Differences between the Hemodialysis and Peritoneal Dialysis Three treatments a week for about 4 hours. Dialysis center. In communities; may require travel in some rural areas. No equipment or supplies in the home. Home Hemodialysis More flexibility in determining your schedule of treatments. Home. More widely used as smaller and simpler machines are developed. Hemodialysis machine connected to plumbing, chair. Ambulatory Peritoneal dialysis (CAPD) Four to six exchanges a day, every day. Any clean environment that allows solution exchanges. Widely available. Bags of dialysis solution take up storage space. Peritoneal Dialysis 3 to 5 exchanges a night, every night, with an additional exchange begun first thing in the morning. Any clean environment that allows solution exchanges. Widely available. Cycling machine, bags of dialysis solution