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this subject is biomaterials please answer all the questions MD 7 7 (20pts). A hydrophobic polyanhydride polymer is used by biomedical engineer for controlled drug

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this subject is biomaterials please answer all the questions

MD 7

7 (20pts). A hydrophobic polyanhydride polymer is used by biomedical engineer for controlled drug release because the engineer anticipates a zero order release that'd be independent of water diffusion into the bulk of the drug carrying polyanhidride. Knowing that the rate of drug release will depend on mass loss, A. Write the differential equation which will govern the rate of mass loss B. Assuming a 1-D surface erosion by hydrolytic degradation, and the degradation rate constant to be 0.002mg/min, how many grams of the polyanhydride drug carrying polymer will remain after 24 hrs if the initial polymer-drug amount was 100 mg? C. How long will it take for half of the drug to get eroded? D. How long will it take for all the drug to be eroded

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