To test for normality, use qqplot by MATLAB. Describe the effect of each treatment regimen on changes in heart rate and blood pressure. Does the distribution of changes in these parameters look normal or not?

NIFED.DOC

Variable Column Description Code

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Id 1-2 ID

trtgrp 4 Treatment group N=nifedipine/P=placebo

bashrtrt 6-8 Baseline heart rate* beats/min

lv1hrtrt 10-12 Level 1 heart rate+ beats/min

lv2hrtrt 14-16 Level 2 heart rate beats/min

lv3hrtrt 18-20 Level 3 heart rate beats/min

bassys 22-24 Baseline systolic bp* mm Hg

lv1sys 26-28 Level 1 systolic bp mm Hg

lv2sys 30-32 Level 2 systolic bp mm Hg

lv3sys 34-36 Level 3 systolic bp mm Hg

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* Immediately prior to randomization.

+ Highest heart rate and systolic blood pressure at baseline and each level of

therapy respectively.

Values of 999 indicates that either

(a) the patient withdrew from the study prior to entering this level of therapy

(b) the patient achieved pain relief prior to reaching this level or therapy,

(c) the patient encountered this level of therapy, but this particular piece

of data was missing.

ID	trtgrp	bashrtrt	lv1hrtrt	lv2hrtrt	lv3hrtrt	bassys	lv1sys	lv2sys	lv3sys
1	P	60	70	64	999	128	110	120	999
2	N	52	64	98	999	180	156	160	140
3	P	100	94	999	999	190	140	999	999
4	N	84	88	96	112	136	126	122	110
5	P	56	70	61	64	230	150	130	150
6	P	105	120	999	999	142	150	999	999
7	N	116	116	999	999	210	230	999	999
8	N	68	68	72	84	170	150	150	156
9	P	85	88	90	92	150	134	140	154
10	N	64	60	999	999	140	120	999	999
11	N	76	90	999	999	160	164	999	999
12	N	88	125	140	999	150	140	140	999
13	P	88	78	80	72	130	120	108	118
14	P	96	114	999	88	152	144	999	158
15	P	54	60	52	58	100	100	92	110
16	P	60	62	68	60	170	180	206	188
17	N	56	58	56	60	110	112	102	110
18	N	56	60	999	999	120	120	999	999
89	N	54	60	78	76	125	120	118	118
20	N	60	60	999	999	230	170	999	999
21	P	60	54	60	64	100	120	130	116
22	N	92	100	100	100	124	134	146	180
23	P	72	84	84	999	168	178	140	999
24	N	100	96	999	999	110	116	999	999
25	P	100	90	113	999	150	130	128	999
26	N	52	74	88	66	164	144	128	140
27	N	76	76	999	999	170	170	999	999
28	P	75	75	75	88	152	152	150	150
29	P	58	58	58	58	999	999	999	999
30	N	56	54	999	59	106	124	999	120
31	P	70	60	999	999	160	180	999	999
32	N	51	66	999	999	150	136	999	999
33	P	90	98	999	999	180	180	999	999
34	N	90	86	999	999	160	140	999	999