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Triiodo aromatics are used as X-ray contrast agents. 3 of these are shown here: COOH COOH COOH I I NH2 H, NH2 HOOC NH2 3-amino-2,4,6-
Triiodo aromatics are used as X-ray contrast agents. 3 of these are shown here: COOH COOH COOH I I NH2 H, NH2 HOOC NH2 3-amino-2,4,6- triiodobenzoic acid 3,5-diamino-2,4,6- triiodobenzoic acid 5-amino-2,4,6- triiodoisophthalic acid 3-Amino-2,4,6-triiodobenzoic acid is synthesized from benzoic acid in 3 steps: COOH COOH COOH COOH 5-66 (1) (2) (3) ICI NO2 NH2 NH2 3-amino benzoic acid 3-amino-2,4,6- triiodobenzoic acid A): shows the reagents to be used in steps 1 and 2. B): Solder monochloride (ICI) can be prepared by mixing equivalent amounts of 12 and Cl2 suggest a reaction mechanism (use arrows) for the iodination of 3-aminobenzoic acid. C): how to produce 3,5-diamino-2,4,6-triiodobenzoic acid from benzoic acid instead
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