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Tyrosine can be converted to glycine in a PLP-dependent reaction. Careful examination of the active site reveals that the CaCH2 bond is in the plane

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Tyrosine can be converted to glycine in a PLP-dependent reaction. Careful examination of the active site reveals that the CaCH2 bond is in the plane of the pi system (perpendicular to the CC bonds of the cofacton). a. Propose the mechunium for this reaction. feel free to start with tyrosine bonded to the cofactor as we have seen with other reactions (10 points) b. The product of this reaction can subsequently be reduced by a different encyme in an NADH-dependent reaction. Propose a mechanism for this reaction. (7 points) Tyrosine can be converted to glycine in a PLP-dependent reaction. Careful examination of the active site reveals that the CaCH2 bond is in the plane of the pi system (perpendicular to the CC bonds of the cofacton). a. Propose the mechunium for this reaction. feel free to start with tyrosine bonded to the cofactor as we have seen with other reactions (10 points) b. The product of this reaction can subsequently be reduced by a different encyme in an NADH-dependent reaction. Propose a mechanism for this reaction. (7 points)

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