Question
Use the paragraph below to answer questions : Animal studies have shown that an acute stressor in close temporal proximity to immune challenge can enhance
Use the paragraph below to answer questions :
Animal studies have shown that an acute stressor in close temporal proximity to immune challenge can enhance the response to delayed-type hypersensitivity and antibody response to vaccination. The current study examined the effect of acute exercise or mental stress prior to influenza vaccination on the subsequent antibody response. Sixty young healthy adults (31 men, 29 women) were randomly allocated to one of three task conditions: dynamic exercise, mental stress, or control. After an initial baseline, participants completed their allocated 45min task and then received the influenza vaccine. Plasma cortisol and interleukin-6 were determined at the end of baseline, after the task, and after 60 min recovery. Antibody titres were measured prevaccination and at 4 weeks and 20 weeks post-vaccination follow-ups. Women in both the exercise and mental stress conditions showed higher influenza antibody titres at both 4 and 20 weeks than those in the control condition, while men responded similarly in all conditions. Interleukin-6 at +60min recovery was found to be a significant predictor of subsequent influenza antibody response in women. In line with animal research, the current study provides preliminary evidence that acute stress can enhance the antibody response to vaccination in humans.
Which of the following variables is an effect modifier of the relationship between the exposure and outcome?
Group of answer choices
Gender
Influenza antibody response
Group assignment (dynamic exercise, mental stress, or control)
Influenza vaccination
None of the listed answers
Step by Step Solution
There are 3 Steps involved in it
Step: 1
Get Instant Access to Expert-Tailored Solutions
See step-by-step solutions with expert insights and AI powered tools for academic success
Step: 2
Step: 3
Ace Your Homework with AI
Get the answers you need in no time with our AI-driven, step-by-step assistance
Get Started