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Use the Star alignment algorithm to compute a multiple sequence alignment ( MSA ) for the sequences: Sequence 1 : AGTCCT Sequence 2 : ACTGTTC
Use the Star alignment algorithm to compute a multiple sequence alignment MSA for the sequences:
Sequence : AGTCCT
Sequence : ACTGTTC
Sequence : CCGCGTT
Sequence : GGGTCCT
The scoring scheme is for a match, for a mismatch, and for a gap penalty.
Recall that the Star alignment first computes a central sequence that has the smallest sum of distances to all other sequences use highest sum of alignment scores with other sequences Then all sequences are pairwise aligned to the star sequence, and these alignments are extended to form a multiple sequence alignment. Show the steps in the algorithm, report the MSA and compute its sum of pairs alignment score.
Use the Clustal algorithm to align the following DNA sequences:
Sequence : ATCGTAC
Sequence : ATGCT
Sequence : ACGTACT
The scoring scheme is for a match, for a mismatch, and for a gap penalty. Show the steps in the algorithm, report the MSA and compute its sum of pairs alignment score.
NOTE: use the sumofpair score instead of the distance score and make the necessary adjustements.
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