Answered step by step
Verified Expert Solution
Link Copied!

Question

1 Approved Answer

use the sum of pair score instead of distance score and make the necessary adjustmints,please solve it in details and show all the steps: 4

use the sum of pair score instead of distance score and make the necessary adjustmints,please solve it in details and show all the steps:
4-Use the Star alignment algorithm to compute a multiple sequence alignment (MSA) for the sequences:
Sequence 1: AGTCCT
Sequence 2 : ACTGTTC
Sequence 3: CCGCGTT
Sequence 4 : GGGTCCT
The scoring scheme is +1 for a match, -1 for a mismatch, and -2 for a gap penalty.
Recall that the Star alignment first computes a central sequence that has the smallest sum of distances to all other sequences (use highest sum of alignment scores with other sequences). Then all sequences are pairwise aligned to the star sequence, and these alignments are extended to form a multiple sequence alignment. Show the steps in the algorithm, report the MSA and compute its sum of pairs alignment score.
5-use the ClustalW algorithm to align the following DNA sequences:
Sequence 1: ATCGTAC
Sequence 2: ATGCT
Sequence 3: ACGTACT
The scoring scheme is +1 for a match, -1 for a mismatch, and -2 for a gap penalty. Show the steps in the algorithm, report the MSA and compute its sum of pairs alignment score.
image text in transcribed

Step by Step Solution

There are 3 Steps involved in it

Step: 1

blur-text-image

Get Instant Access to Expert-Tailored Solutions

See step-by-step solutions with expert insights and AI powered tools for academic success

Step: 2

blur-text-image

Step: 3

blur-text-image

Ace Your Homework with AI

Get the answers you need in no time with our AI-driven, step-by-step assistance

Get Started

Recommended Textbook for

Databases Demystified

Authors: Andrew Oppel

1st Edition

0072253649, 9780072253641

More Books

Students also viewed these Databases questions