Use www.swissadme.ch and draw labetalol into the molecular sketcher including the Boiled Egg model. Modify the labetalol molecule to improve physicochemical properties and submit the two molecules (labetalol and your new derivative) again. Repeat the process with multiple derivatives to see which functional modifications improve labetalol the most is optional. Describe the differences: 1. How did you change the structure? 2. Why did you make the structural changes? 3. How did the structural changes impact physicochemical properties: (LIPO, SIZE, POLAR, INSOLU) 4. How did your molecule perform in regard to synthetic accessibility? 5. How did your molecule perform in regard to the Boiled Egg model and CYP liability? I appreciate your help