Answered step by step
Verified Expert Solution
Link Copied!

Question

1 Approved Answer

Using R language to do the question A recently developed drug, MediCo, has been used over the past 12 months to treat a potentially fatal

image text in transcribed
Using R language to do the question A recently developed drug, MediCo, has been used over the past 12 months to treat a potentially fatal disease. MediCo was approved by a medical regulator last year following initial trials and mortality data has been collected over the past 12 months, since approval, to continue reviewing the drug's effectiveness. This mortality data has been compared with mortality data collected from infected patients, prior to MediCo's approval, who were NOT administered the drug. It is suspected that gender may be a significant covariate on the mortality rate of infected patients. Data Life Drug Gender Status Time 85 67 10 283 0 0 0 0 0 0 0 06 58 108 9 160 23 Life Unique patient identifier (integers 1, 2, .., 4,400) Drug Drug indicator (1 = received drug, 0 = did not receive drug) Gender Gender indicator (1 = female, 0 = male) Status Status indicator (1 = death due to disease, 0 = censoring event occurred) Time Duration in days at which death/censoring occurred (integers with a range of 1-365, with 1 = first day of the investigation and 365 = last day of the investigation). e) Estimate a Cox proportional hazards model with death as the event of interest using the two covariates, drug, and gender, with no interaction term, pasting your results into your answer script. f) Comment on the results produced in part (e) with reference to the effects of the two covariates, drug and gender, on the mortality rate. g) Update the Cox proportional hazards model in part (e) to include an interaction term between drug and gender, pasting your results into your answer script. h) Analyse the effectiveness of MediCo, commenting on any differences between males and females

Step by Step Solution

There are 3 Steps involved in it

Step: 1

blur-text-image

Get Instant Access to Expert-Tailored Solutions

See step-by-step solutions with expert insights and AI powered tools for academic success

Step: 2

blur-text-image_2

Step: 3

blur-text-image_3

Ace Your Homework with AI

Get the answers you need in no time with our AI-driven, step-by-step assistance

Get Started

Recommended Textbook for

Hyers-Ulam Stability Of Ordinary Differential Equations

Authors: Arun Kumar Tripathy

1st Edition

1000386902, 9781000386905

More Books

Students also viewed these Mathematics questions

Question

Compute the equivalent units with respect to conversion.

Answered: 1 week ago

Question

Describe the major barriers to the use of positive reinforcement.

Answered: 1 week ago