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Using this PK Profile Plot with already set parameters, what would be the dose and schedule over 14d. Addition information given: plasma concentrations need to
Using this PK Profile Plot with already set parameters, what would be the dose and schedule over 14d. Addition information given: plasma concentrations need to be greater or equal to 3 units, but not exceed 8 units as toxicity occurs.
I am not sure I am understanding how to figure out the dose and dosing schedule by this plot. Pharmacokinetics is confusing in general for me and looking for help.
Parameterization: Clearance Absorption: 1st order, delay = none, Rate constant = 0.5 Distribution: Compartments = 1, Volume = 10 Elimination: Linear, Clearance = 4 20- 15- 8 10 05 00 time Parameterization: Clearance Absorption: 1st order, delay = none, Rate constant = 0.5 Distribution: Compartments = 1, Volume = 10 Elimination: Linear, Clearance = 4 20- 15- 8 10 05 00 time Step by Step Solution
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