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WE WI Study or Subgroup Events Total Events Total Weight Rate ratio (95% CI) Sergio Cadoni et al.2017 201 408 177 408 57.8% 1.14 [0.98,

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WE WI Study or Subgroup Events Total Events Total Weight Rate ratio (95% CI) Sergio Cadoni et al.2017 201 408 177 408 57.8% 1.14 [0.98, 1.32] Yu-Hsi Hsieh et al.2014 51 90 41 90 13.4% 1.24 [0.93, 1.66] Yu-Hsi Hsieh et al.2017 108 217 88 217 28.8% 1.23 [1.00, 1.51] Total (95% CI) 715 715 100.0% 1.18 [1.05, 1.32] Total events 360 306 Heterogeneity: Chi = 0.52, df = 2 (P = 0.77); 1= 0% Test for overall effect: Z = 2.85 (P = 0.004) 0.1 0.2 0.5 10 Favors WE group Favors WI group A) Explain what this figure represents B) What does the key statistical result of rate ratio (RR) 1.18 actually mean C) What does the key statistical result of 95% CI 1.05, 1.32 actually mean

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