Question
For the following acid-catalyzed tandem Friedel-Crafts alkylation/cyclization reaction, please: 1) Draw the disconnection (for retrosynthesis) of the product to get the appropriate synthons 2) Draw
For the following acid-catalyzed tandem Friedel-Crafts alkylation/cyclization reaction, please:
1) Draw the disconnection (for retrosynthesis) of the product to get the appropriate synthons
2) Draw the arrow-pushing mechanism for each step of the reaction to produce the given product
2) State the type of cyclization that occurs according to Baldwin's rule
Please use drawings (not just written explanations) because I really struggle to understand cyclic reactions without visual representation. Thank you so much!!
LOH CF3COH (20% mol) DCE, 80 C NH
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