What kind of study is this What are the exposure and outcome in this study What is the prevalence of working in the relevant buildings What is the prevalence of heartburn Based on these numbers, which type of observational trial would you expect to be most appropriate in this case Perform a statistical test for association between exposure and outcome and write your conclusion What is the odds ratio The city does a case control study with 200 subjects, taking an equal number of cases and controls They discovered 14 of the cases were exposed and 6 of the controls were exposed Construct the 22 contingency table, perform a statistical test for association between exposure and outcome, and write your conclusion What is the odds ratio The city does a cohort study with 200 subjects, taking an equal number of exposed and unexposed individuals who do not yet have heartburn They discover 75 of the exposed subjects develop heartburn over the next year, compared to 54 of the unexposed subjects Construct the 22 contingency table, perform a statistical test for association between exposure and outcome, and write your conclusion What is the odds ratio Compare the odds ratios and p values you obtained for all three studies Which study design was best in this case For a cohort study, the odds ratio is not typically used to describe the effect size what is usually used instead is called the risk ratio (RR) , which is defined as the proportion of exposed subjects who have the outcome of interest divided by the proportion of unexposed subjects who have the outcome Calculate the risk ratio for the cohort study from part (f) and compare it to the odds ratio A city is worried about the water quality in several buildings in the downtown area They believe that something in the water in those buildings might be causing irritation in the esophagus leading to excessive cases of heartburn They perform a survey of 200 people who work in the downtown area and discover the following data Have heartburn Yes No Total Yes 15 5 20 Work in relevant buildings No 97 83 180 Total 112 88 200 A city is worried about the water quality in several buildings in the downtown area They believe that something in the water in those buildings might be causing irritation in the esophagus leading to excessive cases of heartburn They perform a survey of 200 people who work in the downtown area and discover the following data Have heartburn Yes No Total Yes 15 5 20 Work in relevant buildings No 97 83 180 Total 112 88 200

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What kind of study is this? What are the exposure and outcome in this study? What is the prevalence of working in the relevant buildings?

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What kind of study is this?

What are the exposure and outcome in this study?

What is the prevalence of working in the relevant buildings? What is the prevalence of heartburn? Based on these numbers, which type of observational trial would you expect to be most appropriate in this case?

Perform a statistical test for association between exposure and outcome and write your conclusion. What is the odds ratio?

The city does a case-control study with 200 subjects, taking an equal number of cases and controls. They discovered 14% of the cases were exposed and 6% of the controls were exposed. Construct the 22 contingency table, perform a statistical test for association between exposure and outcome, and write your conclusion. What is the odds ratio?

The city does a cohort study with 200 subjects, taking an equal number of exposed and unexposed individuals who do not yet have heartburn. They discover 75% of the exposed subjects develop heartburn over the next year, compared to 54% of the unexposed subjects. Construct the 22 contingency table, perform a statistical test for association between exposure and outcome, and write your conclusion. What is the odds ratio?

Compare the odds ratios and p-values you obtained for all three studies. Which study design was best in this case?

For a cohort study, the odds ratio is not typically used to describe the effect size; what is usually used instead is called the risk ratio (RR), which is defined as the proportion of exposed subjects who have the outcome of interest divided by the proportion of unexposed subjects who have the outcome. Calculate the risk ratio for the cohort study from part (f) and compare it to the odds ratio.

A city is worried about the water quality in several buildings in the downtown area. They believe that something in the water in those buildings might be causing irritation in the esophagus leading to excessive cases of heartburn. They perform a survey of 200 people who work in the downtown area and discover the following data: Have heartburn Yes No Total Yes 15 5 20 Work in relevant buildings No 97 83 180 Total 112 88 200 A city is worried about the water quality in several buildings in the downtown area. They believe that something in the water in those buildings might be causing irritation in the esophagus leading to excessive cases of heartburn. They perform a survey of 200 people who work in the downtown area and discover the following data: Have heartburn Yes No Total Yes 15 5 20 Work in relevant buildings No 97 83 180 Total 112 88 200