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what ways do chromosomal abnormalities, such as chromosomal mosaicism, ring chromosomes, and marker chromosomes, challenge our understanding of chromosomal biology, genetic diagnosis, and personalized medicine,

what ways do chromosomal abnormalities, such as chromosomal mosaicism, ring chromosomes, and marker chromosomes, challenge our understanding of chromosomal biology, genetic diagnosis, and personalized medicine, and how do emerging genomic technologies enable the characterization and interpretation of complex chromosomal variations? 

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