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When assessing if the difference between two means is statistically signficant, which of these assumptions should you choose as a default option (e.g., in StatTools)

When assessing if the difference between two means is statistically signficant, which of these assumptions should you choose as a default option (e.g., in StatTools) if no information is provided? (assume the means are independent)

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a. Equal variances

b. Unequal variances

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