When Proteins Fall Apart-Denaturing Denaturing is the disruption of the interactions in secondary, tertiary, and quaternary structure. Primary structure remains intact since it has covalent bonds, while the other structures have weaker interactions holding them together. 12. Egg has protein. a. Does a raw egg have the same properties as a fried egg? b. How was this protein denatured? 13. What other way can you denature proteins? a. alcohol: disrupts hydrogen bonding between amine groups b. acid and bases: disrupt c. heavy metal salts: disrupt d. reducing agents: disrupt disulfide bonds 14. Biochemists often say form follows function. What do you predict will happen if the form (secondary, tertiary, and quaternary structure) is disrupted? Enzymes-Biological Catalysts Back in the Chemical Reactions chapter we talked about catalysts -"coupons" for a chemical reaction. Enzymes are biological cataysts. Use the figure and your knowledge of catalyst to complete the chart. An enzyme: Activation energy without enzyme Activation energy with enryme the rate of a biological reaction. Reactants the energy of activation. Products used up during the Progress of reaction reaction.