Which of the following research descriptions would be appropriately addressed with a paired samples t-test?

Which of the following research descriptions would be appropriately addressed with a paired samples t-test? O A randomized clinical trial involved the testing of an experimental drug on cholesterol reduction. 100 subjects were randomized to either: 100mg or 50mg. The dependent variable was the percent reduction in cholesterol. The research question was: Is there a difference in cholesterol reduction between the two groups? 0 A cohort of patients being treated at a clinic were asked to complete the SF-36, a health questionnaire that yields a score from 0-100, where higher scores represent better health, They were assessed at the beginning of their treatment and again at follow-up. The research question was: Is there a difference in health between the baseline and follow-up assessments? O A cohort of patients being treated at a clinic were asked to complete the SF-36, a health questionnaire that yields a score from 0-100, where higher scores represent better health, The researchers also assessed their cholesterol levels. The research question was: Is there an association between health and cholesterol levels