Which of the following statements about Noninferiority studies are true? Select all that apply. Select one or more: A. Because the research purpose in noninferiority studies is clear, the research design and interpretation of study results are straight forward. B. They are used to determine the new treatment is not worse than the standard treatment. C. They are used to compare the difference between a new treatment and a placebo. D. They are used because the new treatment is safer, more convenient, fewer side effects, or less costly