You aim to achieve a steady $10nM$ plasm concentration of a $75$kDa protein. What dosing

strategy should you use to administer the molecule? You have the following data from pilot

experiments: a $1g$ tracer dose of protein yields an area under the curve of plasm

concentration versus time equal to $10g*h\frac{r}{L}$; and the volume of distribution is determined to

be $5L.$

$($Hint: This equation is slightly different from what was shown in the class, but we can convert

the two compartment equations into a single compartment equation using $V_D$ instead of using $V_p$

and $V_t.$ This means, the overall drug clearance can be written as$,\frac{d([c_p]V_D)}{dt}=-k[C_p]V_D.$ Using

this equation and AUC, you can estimate $k.)$