Francis McHenry, 53 years old, has developed partial seizure epilepsy as a consequence of a serious head

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Francis McHenry, 53 years old, has developed partial seizure epilepsy as a consequence of a serious head injury. His seizures have not been controlled well with carbamazepine and sodium valproate.

His doctor adds lamotrigine and later gabapentin to his therapy. His seizures are now controlled well.

What are the possible problems associated with the multidrug treatment of Mr McHenry’s epilepsy?

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