The glucorticoid response element (GRE) has two copies of the sequence 5-AGRACA-3, where R is a purine.
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The glucorticoid response element (GRE) has two copies of the sequence 5′-AGRACA-3′, where R is a purine. Given that the size of the human genome is about 3 billion bp, how many times would you expect this sequence to occur, due to random chance? Would the glucocorticoid receptor bind to all of those sites? Why or why not?
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