=+32. Suppose in the Wright-Fisher model of Example 7.3.2 that each sampled a1 allele has a chance

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=+32. Suppose in the Wright-Fisher model of Example 7.3.2 that each sampled a1 allele has a chance of u of mutating to an a2 allele and that each sampled a2 allele has a chance of v of mutating to an a1 allele, where the mutation rates u and v are taken from (0, 1). If the number Zn of a1 alleles at generation n equals i, then show that Zn+1 is binomially distributed with success probability pi = i 2m(1 − u) + 2m − i 2m v.

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