Suppose we assume that the synonymous and non synonymous rates are both equal to the same value
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Mutation rates differ depending on whether changing the nucleotide base changes the amino acid (non synonymous sites) or not (synonymous sites). A piece of DNA has 200 non synonymous sites with 12 mutations and 100 synonymous sites with 15 mutations. Our goal is to estimate the mutation rate.
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Related Book For
Modeling the Dynamics of Life Calculus and Probability for Life Scientists
ISBN: 978-0840064189
3rd edition
Authors: Frederick R. Adler
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