The first step in eq. 10.26 really involves two reactions, addition of ammonia to the carbonyl carbon

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The first step in eq. 10.26 really involves two reactions, addition of ammonia to the carbonyl carbon to form an ammonium alkoxide followed by a proton transfer from the nitrogen to the alkoxide oxygen. Illustrate this process with equations using the arrow-pushing formalism. The second step in eq. 10.26 also involves two steps, elimination of an alkoxide (RʹO-) followed by deprotonation of the hydroxyl group. Write a detailed mechanism for these steps.

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Organic Chemistry A Short Course

ISBN: 978-1111425562

13th edition

Authors: Harold Hart, Christopher M. Hadad, Leslie E. Craine, David J. Hart

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